Angiotensin II does not influence expression of sarcoplasmic reticulum Ca 2 + ATPase in atrial
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چکیده
http://jra.sagepub.com/content/10/3/121 The online version of this article can be found at: DOI: 10.1177/1470320309342732 2009 10: 121 originally published online 17 July 2009 Journal of Renin-Angiotensin-Aldosterone System Chia-Ti Tsai Cho-Kai Wu, Chuen-Den Tseng, Yin-Tsen Huang, Chia-Shan Hsieh, Wei-Shan Tsai, Jiunn-Lee Lin, Fu-Tien Chiang and myocytes Angiotensin II does not influence expression of sarcoplasmic reticulum Ca2 + ATPase in atrial
منابع مشابه
Long-term endothelin receptor antagonist administration improves alterations in expression of various cardiac genes in failing myocardium of rats with heart failure.
BACKGROUND We reported that long-term (3-month) treatment with the endothelin (ET) type A (ET(A)) receptor antagonist BQ-123 markedly improved survival in rats with chronic heart failure (CHF). However, it is not known whether long-term treatment with an ET receptor antagonist improves alterations in the expression of cardiac genes in failing hearts. METHODS AND RESULTS CHF rats and control s...
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متن کاملSarcoplasmic reticulum Ca2+ transport and gene expression in congestive heart failure are modified by imidapril treatment.
This study was designed to test the hypothesis that blockade of the renin-angiotensin system improves cardiac function in congestive heart failure by preventing changes in gene expression of sarcoplasmic reticulum (SR) proteins. We employed rats with myocardial infarction (MI) to examine effects of an angiotensin-converting enzyme inhibitor, imidapril, on SR Ca(2+) transport, protein content, a...
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The multifunctional Ca(2+)/calmodulin-dependent kinase II (CaMKII) is activated by vasoconstrictors in vascular smooth muscle cells (VSMC), but its impact on vasoconstriction remains unknown. We hypothesized that CaMKII inhibition in VSMC decreases vasoconstriction. Using novel transgenic mice that express the inhibitor peptide CaMKIIN in smooth muscle (TG SM-CaMKIIN), we investigated the effec...
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